This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Gottlieb, J. Search for Related Content PubMed PubMed Citation Articles by Gottlieb, J. Social Bookmarking                   What's this?

Review: Update on lung transplantation

Hannover Medical School Dpt. Respiratory Medicine OE 6870 Carl Neuberg-Str. 1 30625 Hannover, Germany, gottlieb.jens @mh-hannover.de

Lung transplantation is a suitable treatment to improve the quality of life and the prognosis of patients with various end-stage pulmonary diseases. There is a shortage of organs and the number of patients on waiting list is exceeding the number of transplants per year approximately two-fold in most countries. Strategies to increase the donor pool are therefore crucial. The long-term prognosis after lung transplantation is not yet as good as for other transplantation procedures and special complications should be taken into account. Aside from infections chronic organ dysfunction is the main cause of death and the most important prognosis limiting factor. Other typical problems are rejection, bronchus complications, and primary transplant dysfunction. However, the results of large centers show promising improvements in recent years.

Key Words: Lung transplantation • graft rejection • immunosuppression • bronchiolitis obliterans • patient selection

Therapeutic Advances in Respiratory Disease, Vol. 2, No. 4, 237-247 (2008)
DOI: 10.1177/1753465808093514


CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?